WEEK 6-Hyperglycemia

The type 2 diabetes is a chronic condition in which the pancreas produce little or no insulin. This disease can be treated but has no cure and can last for years or your entire life. Medical reinforcement consists of controling bood sugar levels. Also difference with diabetes 1 is that diabetes 2 increases body mass, type 1 keeps you slim

Obesity is now carbonated associated with chronic low-grade inflammation that, without intervention, contributes to the development of prediabetes and eventually type 2 diabetes. These results reveal a new role for CD27-CD70 interactions in the pathogenesis of type 2 diabetes and provide support for future research on this pathway.

i think obesity is now strongly associated with chronic low grade inflammation that, without intervention, contributes to the development of pre-diabetes and eventually Type 2 diabetes. The CD27-CD70 pathway provides a crucial inflammatory co-stimulatory signal, with CD70 being expressed on activated antigen presenting cells, and CD27 expressed on lymphocytes. I am very sure that with advances in biotechnology and health sciences, many of these diseases will no longer be classified as "incurable".

Obesity is a condition that alters the metabolism to the point of generating hyperglycemia which is a problem that if not controlled, could end up triggering type 2 diabetes mellitus. This disease is caused by the high concentration of glucose in the blood, which is generated by the food imbalance suffered by the world population.

I believe that type 2 diabetes will be incurable but it is controllable depending on each person, it is important that people take this disease seriously because in an oversight can lead to death, but with the joint operation of CD27 and CD70 is good news because it is a breakthrough for diabetes and for prediabetic people.

I think laboratory tests play a

important role in distinguishing between prediabetes and diabetes, which in turn helps in disease management and even possible disease reversal. In addition, prediabetes is a condition that when addressed promptly and effectively, they can be reversed to prevent it from developing into diabetes.

In my opinion, it is important to inform people with obesity about type 2 diabetes since it is an incurable disease and that could lead to death, but with the CD27-CD70 it could help a lot to prediabetic people.

The type 2 diabetes is the most common form of diabetes and is chronic because it lasts a lifetime, there is prediabetes that requires treatment and a change in lifestyle. The study of CD27 and CD70 working together is a breakthrough for diabetes

Nowadays obesity is a problem that affects the whole world and because of it more than 400 million people suffer from diabetes worldwide according to the WHO. Being overweight and obese increase a person's risk of getting type 2 diabetes.

So, with this research, we can understand how our body reacts to diabetes, but it is in our hands to avoid contracting this disease that to this day has no cure.

- Melany Vallejos Lujan

My opinion about the article is that dendritic cells play an important role in the activation of CD4 T cells due to their interaction in the presentation of antigens to T cells, for this they need

costimulators to induce efficient T cell responses, such as the stimulatory molecule CD70, which is the only known ligand for the CD27 receptor.

It is this CD70 that according to research regulates sugar increases, in cases of diabetics.

Diabetes is a disease that has no cure. But prediabetes can be treated and reversed, but very few people know they have prediabetes. Laboratory tests are very important in diagnosing diabetes and prediabetes, helping to treat or reverse the disease.